import sounddevice as sd
from scipy.io.wavfile import write

fs = 16000  # Sample rate
seconds = 5  # Duration of recording

myrecording = sd.rec(int(seconds * fs), samplerate=fs, channels=1)
sd.wait()  # Wait until recording is finished
write('output.wav', fs, myrecording)  # Save as WAV file

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simpleaudio
portaudio
sounddevice